Estimated exposure to endotoxin and circulating immunological markers among male farmers in the Biomarkers of Exposure and Effect in Agriculture study
Ezennia S, Freeman L, Chang V, Xie S, Sandler D, Andreotti G, Parks C, Friesen M, Hofmann J. Estimated exposure to endotoxin and circulating immunological markers among male farmers in the Biomarkers of Exposure and Effect in Agriculture study. Occupational And Environmental Medicine 2024, 81: 635-638. PMID: 39746796, PMCID: PMC11821429, DOI: 10.1136/oemed-2024-109646.Peer-Reviewed Original ResearchConceptsExposure to endotoxinImmune markersAssociated with reduced lung cancer riskEndotoxin exposureEstimated geometric mean ratiosCirculating immune markersMacrophage-derived chemokine/CCL22Reduced risk of lung cancerLevels of fibroblast growth factor-2Decreased levelsMultiplex bead-based assayRisk of lung cancerExposure-response mannerExposed to endotoxinAssociated with increased levelsLung cancer riskFibroblast growth factor-2Immunological alterationsGrowth factor 2Serum levelsImmunological markersSIL-4RLung cancerBead-based assayMultivariate linear regression
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